Strategic preparation of tetraconazole from PTFE waste: Addressing the impending PFAS regulations

Authors: Weikang Lin 1, *, Puivun Chai 1, Lei Cao 2, Le Kang 3, Mingxian Chen 4

Affiliations:

1Department of Chemical and Petroleum Engineering, Faculty of Engineering Technology and Built Environment, UCSI University, Kuala Lumpur, Malaysia
2Department of Oncology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Nanjing, China
3School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, China
4Department of Research and Development, Liaoning Longtian Chemical Technology Co., Ltd., Fuxin, China

Abstract

Stricter global regulations on PFAS compounds have created a need for sustainable waste management solutions. In this study, we propose a method to synthesize the fungicide tetraconazole using PTFE waste as a raw material. This approach converts a difficult-to-recycle waste into a valuable product, helping to address environmental challenges. The process involves the controlled pyrolysis of PTFE waste to produce tetrafluoroethylene (TFE), which then reacts with 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-ol (compound 4-b) in a benzotrifluoride solution under optimized conditions. This reaction yields tetraconazole with a GC purity of 99.25%. The findings support circular economy practices and align with emerging strict PFAS regulations.

Keywords

Triazole fungicides, Tetraconazole, PFAS, PTFE waste, Tetrafluoroethylene addition

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DOI

https://doi.org/10.21833/ijaas.2025.09.014

Citation (APA)

Lin, W., Chai, P., Cao, L., Kang, L., & Chen, M. (2025). Strategic preparation of tetraconazole from PTFE waste: Addressing the impending PFAS regulations. International Journal of Advanced and Applied Sciences, 12(9), 152–160. https://doi.org/10.21833/ijaas.2025.09.014