International Journal of Advanced and Applied Sciences
Int. j. adv. appl. sci.
EISSN: 2313-3724
Print ISSN: 2313-626X
Volume 4, Issue 1 (January 2017), Pages: 59-66
Title: Effect of iron deficiency anemia on glycosylated hemoglobin level (HbA1c) in non-diabetic patients in Riyadh region of Saudi Arabia
Author(s): Abdullah Mahal Ghareep Alenazi, Abbas Habeeb Al-Saeed *, Hazem Ghneim, Abjal Pasha Shaik
Affiliation(s):
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia
https://doi.org/10.21833/ijaas.2017.01.009
Abstract:
Iron deficiency anemia (IDA) is associated with higher HbA1c and higher fructose-amine. We proposed to analyze the effects of iron deficiency anemia on HbA1c levels. The aim of this study is to determine the association of IDA and HbA1c levels in non-diabetic patients in Riyadh region of Saudi Arabia in order to understand if IDA is an important factor influencing HbA1c levels in non-diabetics. In this observational case-control study conducted from December 2014 at College of Applied Medical Sciences, KSU, a complete blood count and biochemical analysis of ferritin, vitamin B12, folic acid level and total iron binding capacity with iron levels in 100 diabetic patients with IDA compared to healthy controls will be performed. All subjects will be selected from Riyadh Region of Saudi Arabia. This study revealed that IDA and corresponding CBC parameters along with vitamin B12, folic acid and liver function test parameters cause significant variations in HbA1c levels. In addition, correlations were observed in percentages of hemoglobin, iron, ferritin and fasting glucose with HbA1c levels in male and female subjects without diabetes. This study indicates that closer monitoring of IDA and all these parameters are needed to improve the overall quality of life of subjects. The study results signify that additional thorough cohort and interventional studies are necessary to assess the role of HbA1c with IDA for effective treatment management.
© 2017 The Authors. Published by IASE.
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Anemia, Iron deficiency, HbA1c
Article History: Received 31 October 2016, Received in revised form 18 December 2016, Accepted 20 December 2016
Digital Object Identifier:
https://doi.org/10.21833/ijaas.2017.01.009
Citation:
Alenazi AMG, Al-Saeed AH, Ghneim H, and Shaik AP (2017). Effect of iron deficiency anemia on glycosylated hemoglobin level (HbA1c) in non-diabetic patients in Riyadh region of Saudi Arabia. International Journal of Advanced and Applied Sciences, 4(1): 59-66
http://www.science-gate.com/IJAAS/V4I1/Alenazi.html
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