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 Volume 6, Issue 6 (June 2019), Pages: 30-34


 Original Research Paper

 Title: A comparison of the etiology of early versus late fetal death from a single center

 Author(s): Sarah F. Almutairy 1, *, Amal M. Binhazzaa 2, Mujahid E. Bukhari 1, Ghadeer K. Al-Shaikh 1, Hazem M. Al-Mandeel 1


 1Department of Obstetrics and Gynecology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia
 2ENT Department, King Fahad Medical Center, Riyadh, Saudi Arabia

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 * Corresponding Author. 

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Fetal death is one of the most devastating complications in obstetrics which remained understudied in our population. This study was done to study the maternal and fetal risk factors that lead to fetal death. To compare the rate of different etiologies in early versus late Fetal Death (FD) in cases of FD presented to King Khalid University Hospital, Riyadh, Saudi Arabia. A retrospective cohort study was conducted from 2006-2013 and cases were classified into Early FD (20-33 weeks + 6 days) and late FD (≥34 weeks) groups. A total of 26539 births including 304 cases (1.14%) of FD occurred during the study period. About 24 cases were excluded from the final analyses due to missing records or incorrect coding. The remaining 280 subjects were categorized into early (46.4%) and late (53.6%) IUFD groups. A substantial number of subjects from early (46%) and late (68%) FD groups did not have regular antenatal care. There were no significant differences in the etiology of FD such as obstetric complications, maternal medical diseases, fetal congenital anomalies, umbilical cord abnormalities, and maternal/fetal infections between the two groups. Intrauterine growth restriction (IUGR) and Gestational Diabetes Mellitus (GDM) were significantly associated with late IUFD (41 vs. 18.4% and 20.7 vs. 7.7%, respectively). Placental abnormalities were higher in the late FD group, although the difference was not statistically significant. Fetal death isn’t a rare incidence. IUGR and GDM are significantly associated with increased frequency of late IUFD. Further research is needed for a firm understanding of the incidence of IUFD in Saudi Arabia. 

 © 2019 The Authors. Published by IASE.

 This is an open access article under the CC BY-NC-ND license (

 Keywords: Early intrauterine fetal death, Late intrauterine fetal death, Prevalence, Etiology

 Article History: Received 29 November 2018, Received in revised form 19 March 2019, Accepted 2 April 2019


We would like to acknowledge the support we received from the Deanship of Scientific Research at King Saud University for funding this project through Research Group Project # RGB-VPP-241. We also thank Ms. Bella Rowena B. Magnaye for all the administrative and technical help.

 Compliance with ethical standards

 Conflict of interest:  The authors declare that they have no conflict of interest.


 Almutairy SF, Binhazzaa AM, and Bukhari ME et al. (2019). A comparison of the etiology of early versus late fetal death from a single center. International Journal of Advanced and Applied Sciences, 6(6): 30-34

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